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Sildenafil is an oral drug for the treatment of male erectile dysfunction. It is a phosphodiesterase inhibitor that was originally developed as an antianginal agent but was found to be more effective in the treatment of impotence.

Sildenafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). The physiologic mechanism of erection of the penis involves release of nitric oxide (NO) in the corpus cavernosum during sexual stimulation.

Sildenafil (Viagra®) was the first drug with this mechanism of action to be marketed; it is not a prostaglandin inhibitor. It is administered orally as opposed to other therapies for impotence which require direct injection into the penis or insertion of a urethral suppository.

PRICE TABLE
tablets price price/item
4 x 100 mg   50,00   12,50
10x 100 mg 110,00   11,00
20 x 100 mg 210,00    10,50
30 x 100 mg 300,00    10,00
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